From the Director:


Welcome to the new website for the Duke Cardiovascular Research Center (CVRC). This site provides an overview of the exciting happenings in the Center and a portal for access to many of our programs.

The purpose of the Duke CVRC is to promote and stimulate basic discoveries that will advance understanding of the molecular pathogenesis of cardiovascular diseases. We anticipate that these discoveries will contribute to enhancing clinical care, developing novel diagnostic strategies, and identifying new targets for therapy. To promote our objectives, the Center provides a framework of support for our membership of more than 60 faculty members spanning six academic departments at Duke University and Duke-NUS in Singapore. Through the Center, we have launched a series of programs designed to encourage the development of an interactive and synergistic community of scientists focused on addressing critical problems in cardiovascular disease.

I would like to highlight a few of our programs and support services. All are available to members, while some are also open to the community at large.

  • The Cardiovascular Research Seminar Series held twice a month on Wednesday at 4:00 pm in Room 143 of the Jones Building. The speakers alternate between distinguished visiting scientists and Duke-based investigators who provide a presentation of their research in progress. These CME-approved seminars provide updates and insights from the latest cutting-edge research and serve as a focus for communication and collaborations.
  • The CVRC also hosts an Annual Scientific Retreat, allowing a full day of scientific exchange among our members.
  • In addition, the CVRC also plays a role in developing programs for the annual Cardiovascular Symposium held at Duke as well as corresponding symposia hosted at our sister institution, Duke-NUS in Singapore and sponsored by its Cardiovascular and Metabolic Disorders Research Program.
  • CVRC members also have access to research funding through the Mandel Center for Hypertension and Atherosclerosis at Duke. The Mandel Center was established to advance scientific understanding in the areas of hypertension and atherosclerosis. To promote its mission, the Mandel Center has funded up to five seed grants per year to support innovative research into the causes and treatment of hypertension and atherosclerosis. The hope and expectation is that these grants can be used to generate pilot data that will then lead to larger collaborative grant applications such as NIH RO1’s or PPG’s. Since the Mandel Center was established in 2006, this program has a strong track record of supporting outstanding research in its target areas leading to publications in prestigious journals and new external funding opportunities.
  • To further enhance and support our members, the Duke CVRC also provides funding for infrastructure support. This includes support for
    • Histopathology Core
    • Mouse Phenotyping Core
    • as well as opportunities for matching funds to purchase shared equipment. Links to all these services are available through the website.
We are very excited by the potential of this new Center. Working with our stake holders, including the Mandel Center for Hypertension and Atherosclerosis at Duke, the Duke Division of Cardiology, the Duke Health System, the Duke School of Medicine, and the Cardiovascular and Metabolic Disorders Research Program at Duke-NUS in Singapore, we believe that the Duke CVRC has great potential to promote and enhance basic cardiovascular research.

We invite you to explore our website and learn about the services and opportunities available through the Duke CVRC. We also welcome your comments and suggestions. Finally, we encourage Duke scientists who are working in the broad thematic area of cardiovascular disease to apply for membership by submitting a cover letter stating your research interest and CV to DukeCVRC@dm.duke.edu, which will then be forwarded to our Executive Committee for consideration.

Thank you for your interest in our programs,

Howard Rockman, M.D.
Edward S. Orgain Professor of Cardiology
Director, Duke Cardiovascular Research Center